Determination Of Ascorbic Acid In Vitamin C Tablets
Introduction
Vitamin C or ascorbic acid is a water-soluble vitamin that is essential for human health. It is an antioxidant that plays a vital role in maintaining the immune system, promoting wound healing, and producing collagen. Vitamin C is found in many fruits and vegetables, but it can also be taken as a dietary supplement in the form of tablets.
The determination of ascorbic acid in vitamin C tablets is essential to ensure that the tablets contain the amount of the vitamin that is claimed on the label. The method used to determine the ascorbic acid content of vitamin C tablets is called titration.
Titration
Titration is a chemical analysis technique that involves adding a known amount of a reagent to a sample until a reaction is complete. The point at which the reaction is complete is called the endpoint, and it is usually detected by a change in color or pH.
The most common method used to determine the ascorbic acid content of vitamin C tablets is known as iodometric titration. This method involves the use of iodine as a reagent, which reacts with ascorbic acid to form dehydroascorbic acid and iodide ions.
Procedure
The procedure for determining the ascorbic acid content of vitamin C tablets involves the following steps:
- Weigh the vitamin C tablet and dissolve it in a known amount of water.
- Add a few drops of starch indicator to the solution.
- Titrate the solution with a standardized solution of iodine until the blue color of the iodine-starch complex disappears.
- Note the volume of the iodine solution used.
The amount of ascorbic acid in the tablet can be calculated using the following formula:
Ascorbic acid (mg) = [(V1 - V2) x N x 88] / W
Where:
- V1 = volume of iodine solution used for titration (in mL)
- V2 = volume of iodine solution used for a blank titration (in mL)
- N = normality of the iodine solution
- W = weight of the tablet (in g)
Conclusion
The determination of ascorbic acid in vitamin C tablets is an important quality control measure that ensures that the tablets contain the labeled amount of vitamin C. Titration is a widely used method for the determination of ascorbic acid in vitamin C tablets. The procedure involves the use of iodine as a reagent, and the amount of ascorbic acid in the tablet can be calculated using a simple formula.
Meta Description
Determination of ascorbic acid in vitamin C tablets is essential to ensure that the tablets contain the amount of the vitamin that is claimed on the label. Titration is the most common method used for this purpose. This article explains the procedure for determining the ascorbic acid content of vitamin C tablets using iodometric titration.
Meta Keywords
ascorbic acid, vitamin C, tablets, titration, iodometric, reagent, endpoint, iodine, dehydroascorbic acid, iodide ions, starch indicator, formula, quality control