Causes Of Elevated Vitamin B12 Levels In Child
Vitamin B12 is an essential nutrient that plays a vital role in the proper functioning of the brain and nervous system. It is necessary for the production of red blood cells, DNA, and other vital components of the human body. However, an elevated level of vitamin B12 in children can be a cause of concern for parents and pediatricians alike. In this article, we will explore the various causes of elevated vitamin B12 levels in children.
What is Vitamin B12?
Vitamin B12, also known as cobalamin, is a water-soluble vitamin that is found in animal products such as meat, fish, and dairy. It is essential for the proper functioning of the brain and nervous system and is also involved in the production of red blood cells and DNA.
Vitamin B12 deficiency is a common problem, especially in vegetarians and vegans who do not consume animal products. However, an elevated level of vitamin B12 in children can also be a cause for concern.
Causes of Elevated Vitamin B12 Levels in Children
1. Liver Disease
Liver disease can cause an increase in vitamin B12 levels in children. The liver is responsible for storing and processing vitamin B12, and if it is not functioning correctly, it can lead to an increase in vitamin B12 levels in the blood.
2. Leukemia
Leukemia is a type of blood cancer that can cause an increase in vitamin B12 levels. The abnormal white blood cells produced in leukemia can produce and release large amounts of vitamin B12 into the bloodstream.
3. Polycythemia Vera
Polycythemia vera is a rare blood disorder that causes the body to produce too many red blood cells. This can cause an increase in vitamin B12 levels in the blood.
4. Cobalamin C Deficiency
Cobalamin C deficiency is a rare genetic disorder that affects the body's ability to process vitamin B12. This can cause an increase in vitamin B12 levels in the blood.
5. Excessive Vitamin B12 Supplementation
Excessive vitamin B12 supplementation can cause an increase in vitamin B12 levels in the blood. Vitamin B12 supplements should only be taken under the guidance of a healthcare professional.
6. Inherited Metabolic Disorders
Inherited metabolic disorders such as homocystinuria and methylmalonic acidemia can cause an increase in vitamin B12 levels in the blood.
7. Chronic Myeloid Leukemia
Chronic myeloid leukemia is a type of blood cancer that can cause an increase in vitamin B12 levels. Similar to leukemia, the abnormal white blood cells produced in chronic myeloid leukemia can produce and release large amounts of vitamin B12 into the bloodstream.
Symptoms of Elevated Vitamin B12 Levels in Children
In most cases, elevated vitamin B12 levels do not cause any symptoms in children. However, in some cases, it may cause symptoms such as:
- Loss of appetite
- Nausea
- Vomiting
- Headache
- Fatigue
- Dizziness
Conclusion
Elevated vitamin B12 levels in children can be a cause for concern, and it is important to identify the underlying cause. Liver disease, leukemia, polycythemia vera, cobalamin C deficiency, excessive vitamin B12 supplementation, inherited metabolic disorders, and chronic myeloid leukemia are some of the causes of elevated vitamin B12 levels in children. Parents should consult a pediatrician if they notice any symptoms in their child.